\u00c7ox b\u00f6y\u00fck ehtimalla, aliml\u0259r qad\u0131nlarda \u0259n \u00e7ox yay\u0131lan x\u0259r\u00e7\u0259ng x\u0259st\u0259liyi il\u0259 m\u00fcbariz\u0259d\u0259 k\u00f6m\u0259klik ed\u0259n s\u0259m\u0259r\u0259li d\u0259rman \u0259ld\u0259 etm\u0259y\u0259 nail olacaqlar. Avstraliyan\u0131n Qarri Perkins Tibbi Ara\u015fd\u0131rmalar \u0130nstitutunun aliml\u0259ri a\u015fkar edibl\u0259r ki, bal ar\u0131s\u0131 z\u0259h\u0259rind\u0259ki bir madd\u0259 d\u00f6\u015f x\u0259r\u00e7\u0259ngin\u0259 qar\u015f\u0131 “son d\u0259r\u0259c\u0259 g\u00fccl\u00fc” bir silah olaraq istifad\u0259 edil\u0259 bil\u0259r.<\/p>\n
ARANTV.AZ<\/strong>\u00a0 x\u0259b\u0259r verir ki, k\u0259\u015ffin m\u00fc\u0259llifl\u0259ri son bir ne\u00e7\u0259 ildir ar\u0131 z\u0259h\u0259rinin terapevtik potensial\u0131n\u0131 ara\u015fd\u0131ran Siara Daffinin r\u0259hb\u0259rlik etdiyi t\u0259dqiqat\u00e7\u0131lard\u0131r.<\/p>\n Aliml\u0259r \u0259vv\u0259ll\u0259r ar\u0131 z\u0259h\u0259rind\u0259ki b\u0259zi peptidl\u0259rin v\u0259 z\u00fclallar\u0131n qan beyin baryeri \u00fcz\u0259rind\u0259n d\u0259rman verm\u0259k \u00fc\u00e7\u00fcn istifad\u0259 edil\u0259 bil\u0259c\u0259yini a\u015fkar etmi\u015fl\u0259r. Ancaq Daffi v\u0259 h\u0259mkarlar\u0131n\u0131n i\u015fi, melittin adl\u0131 bal ar\u0131s\u0131 z\u0259h\u0259rinin t\u0259rkibind\u0259ki madd\u0259y\u0259 v\u0259 onun d\u00f6\u015f x\u0259r\u00e7\u0259nginin m\u00fcxt\u0259lif klinik alt n\u00f6vl\u0259rind\u0259 h\u00fcceyr\u0259 \u00f6l\u00fcm\u00fcn\u0259 nec\u0259 s\u0259b\u0259b ola bil\u0259c\u0259yin\u0259 y\u00f6n\u0259lmi\u015fdi.<\/p>\n Daffi izah edib: “Normal ar\u0131 z\u0259h\u0259rini normal d\u00f6\u015f h\u00fcceyr\u0259l\u0259ri v\u0259 klinik d\u00f6\u015f x\u0259r\u00e7\u0259ngi alt tipl\u0259ri \u00fcz\u0259rind\u0259 test etdik: hormon reseptoru m\u00fcsb\u0259t, HER2 (epidermal b\u00f6y\u00fcm\u0259 faktoru reseptoru) z\u0259nginl\u0259\u015fdirilmi\u015f v\u0259 \u00fc\u00e7qat m\u0259nfi d\u00f6\u015f x\u0259r\u00e7\u0259ngi”.<\/p>\n Komanda, ar\u0131 z\u0259h\u0259rinin m\u00fc\u0259yy\u0259n bir konsentrasiyas\u0131ndan x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin y\u00fczd\u0259 100-n\u00fcn \u00f6l\u00fcm\u00fcn\u0259 s\u0259b\u0259b olmaq \u00fc\u00e7\u00fcn istifad\u0259 edil\u0259 bil\u0259c\u0259yini, sa\u011flam h\u00fcceyr\u0259l\u0259rin is\u0259 z\u0259r\u0259rsiz qald\u0131\u011f\u0131n\u0131 a\u015fkar edib. Daffinin s\u00f6zl\u0259rin\u0259 g\u00f6r\u0259, melittin “x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin membranlar\u0131n\u0131 60 d\u0259qiq\u0259 \u0259rzind\u0259 tamamil\u0259 m\u0259hv edir”.<\/p>\n Aliml\u0259r melittin nec\u0259 i\u015fl\u0259diyi bar\u0259d\u0259 bir ne\u00e7\u0259 maraql\u0131 m\u00fc\u015fahid\u0259l\u0259r aparm\u0131\u015flar. Komanda, 20 d\u0259qiq\u0259 \u0259rzind\u0259 birl\u0259\u015fm\u0259nin x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rinin b\u00f6y\u00fcm\u0259si v\u0259 \u00e7oxalmas\u0131 \u00fc\u00e7\u00fcn istifad\u0259 etdiyi b\u0259zi \u0259sas siqnal yollar\u0131n\u0131 bloklad\u0131\u011f\u0131n\u0131 a\u015fkar edib. Melittinin bu reseptorlar\u0131n f\u0259aliyy\u0259tini mane\u0259 t\u00f6r\u0259tm\u0259kl\u0259 \u0259sas kimy\u0259vi mesajlar\u0131 ba\u011flamaq qabiliyy\u0259ti i\u015fd\u0259 \u0259sas tap\u0131nt\u0131 idi.<\/p>\n Siara Daffi: “Bu, t\u0259bii birl\u0259\u015fm\u0259l\u0259rin insan x\u0259st\u0259likl\u0259rini m\u00fcalic\u0259 etm\u0259k \u00fc\u00e7\u00fcn nec\u0259 istifad\u0259 edil\u0259 bil\u0259c\u0259yin\u0259 dair daha bir g\u00f6z\u0259l n\u00fcmun\u0259dir.”<\/p>\n Komanda, eyni zamanda, sintetik melittin formalar\u0131n\u0131 haz\u0131rlay\u0131b v\u0259 onu x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rin\u0259 qar\u015f\u0131 s\u0131naqdan ke\u00e7irib. Sintetik melittinin t\u0259xmin\u0259n eyni d\u0259r\u0259c\u0259d\u0259 t\u0259sirli oldu\u011fu t\u0259sbit edilib. Onun funksiyalar\u0131ndan biri d\u0259 s\u00fcd v\u0259zisi x\u0259r\u00e7\u0259nginin h\u00fcceyr\u0259 membranlar\u0131n\u0131 de\u015fm\u0259kdir, bu s\u0259b\u0259bd\u0259n d\u0259 aliml\u0259r x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rin\u0259 \u00e7atmalar\u0131n\u0131 asanla\u015fd\u0131ran kimy\u0259vi terapiya d\u0259rmanlar\u0131 kimi m\u00f6vcud x\u0259r\u00e7\u0259ng m\u00fcalic\u0259l\u0259ri il\u0259 birlikd\u0259 istifad\u0259 edil\u0259 bil\u0259c\u0259yini ara\u015fd\u0131r\u0131blar.<\/p>\n Daffi deyib: “Melittinin ki\u00e7ik molekullarla v\u0259 ya dosetaksel kimi kimyaterapiya d\u0259rmanlar\u0131 il\u0259 y\u00fcks\u0259k aqressiv d\u00f6\u015f x\u0259r\u00e7\u0259ngi n\u00f6vl\u0259rini m\u00fcalic\u0259 etm\u0259k \u00fc\u00e7\u00fcn istifad\u0259 edil\u0259 bil\u0259c\u0259yini a\u015fkar etdik. Melittin v\u0259 docetaxel birl\u0259\u015fm\u0259si si\u00e7anlardak\u0131 \u015fi\u015fin artmas\u0131n\u0131 azaltmaq \u00fc\u00e7\u00fcn son d\u0259r\u0259c\u0259 s\u0259m\u0259r\u0259li idi”.<\/p>\n \u0130\u015fin m\u00fc\u0259llifl\u0259ri t\u0259dqiqatlar\u0131n yeni ba\u015flad\u0131\u011f\u0131n\u0131, lakin bal ar\u0131s\u0131 z\u0259h\u0259rinin d\u00f6\u015f x\u0259r\u00e7\u0259ngini m\u00fcalic\u0259 etm\u0259k \u00fc\u00e7\u00fcn istifad\u0259 perspektivl\u0259rinin \u00e7ox \u00fcmidverici oldu\u011funu vur\u011fulay\u0131blar.<\/p>\n Bu, x\u00fcsusil\u0259 \u00fc\u00e7qat m\u0259nfi x\u0259r\u00e7\u0259ngin\u0259 aiddir. X\u0259st\u0259liyin y\u00fczd\u0259 15-d\u0259 diaqnoz qoyulur, lakin s\u00fcd v\u0259zisi x\u0259r\u00e7\u0259ngi \u00f6l\u00fcml\u0259rinin t\u0259xmin\u0259n y\u00fczd\u0259 40-n\u0131 t\u0259\u015fkil edir. Son vaxtlara q\u0259d\u0259r bu tip x\u0259r\u00e7\u0259ng x\u0259st\u0259l\u0259ri \u00fc\u00e7\u00fcn yaln\u0131z kimy\u0259vi terapiya g\u00f6st\u0259rilmi\u015fdir.Publika.az<\/p>\n","protected":false},"excerpt":{"rendered":" \u00c7ox b\u00f6y\u00fck ehtimalla, aliml\u0259r qad\u0131nlarda \u0259n \u00e7ox yay\u0131lan x\u0259r\u00e7\u0259ng x\u0259st\u0259liyi il\u0259 m\u00fcbariz\u0259d\u0259 k\u00f6m\u0259klik ed\u0259n s\u0259m\u0259r\u0259li d\u0259rman \u0259ld\u0259 etm\u0259y\u0259 nail olacaqlar. Avstraliyan\u0131n Qarri Perkins Tibbi Ara\u015fd\u0131rmalar \u0130nstitutunun aliml\u0259ri a\u015fkar edibl\u0259r ki, bal ar\u0131s\u0131 z\u0259h\u0259rind\u0259ki bir madd\u0259 d\u00f6\u015f x\u0259r\u00e7\u0259ngin\u0259 qar\u015f\u0131 “son d\u0259r\u0259c\u0259 g\u00fccl\u00fc” bir silah olaraq istifad\u0259 edil\u0259 bil\u0259r. ARANTV.AZ\u00a0 x\u0259b\u0259r verir ki, k\u0259\u015ffin m\u00fc\u0259llifl\u0259ri son bir ne\u00e7\u0259 ildir ar\u0131 z\u0259h\u0259rinin terapevtik potensial\u0131n\u0131 ara\u015fd\u0131ran Siara Daffinin r\u0259hb\u0259rlik etdiyi t\u0259dqiqat\u00e7\u0131lard\u0131r. Aliml\u0259r \u0259vv\u0259ll\u0259r ar\u0131 z\u0259h\u0259rind\u0259ki b\u0259zi peptidl\u0259rin v\u0259 z\u00fclallar\u0131n qan beyin baryeri \u00fcz\u0259rind\u0259n d\u0259rman verm\u0259k \u00fc\u00e7\u00fcn istifad\u0259 edil\u0259 bil\u0259c\u0259yini a\u015fkar etmi\u015fl\u0259r. Ancaq Daffi v\u0259…<\/p>\n","protected":false},"author":2,"featured_media":215958,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"categories":[26],"tags":[],"aioseo_notices":[],"gutentor_comment":0,"rttpg_featured_image_url":{"full":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false],"landscape":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false],"portraits":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false],"thumbnail":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1-150x150.png",150,150,true],"medium":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1-300x169.png",300,169,true],"large":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",640,360,false],"1536x1536":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false],"2048x2048":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false],"post-thumbnail":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1-240x172.png",240,172,true],"advps-thumb-one":["https:\/\/arantv.az\/wp-content\/uploads\/2020\/09\/ari1.png",800,450,false]},"rttpg_author":{"display_name":"V\u00fcsal Rafiqo\u011flu","author_link":"https:\/\/arantv.az\/?author=2"},"rttpg_comment":0,"rttpg_category":"Sosial<\/a>","rttpg_excerpt":"\u00c7ox b\u00f6y\u00fck ehtimalla, aliml\u0259r qad\u0131nlarda \u0259n \u00e7ox yay\u0131lan x\u0259r\u00e7\u0259ng x\u0259st\u0259liyi il\u0259 m\u00fcbariz\u0259d\u0259 k\u00f6m\u0259klik ed\u0259n s\u0259m\u0259r\u0259li d\u0259rman \u0259ld\u0259 etm\u0259y\u0259 nail olacaqlar. Avstraliyan\u0131n Qarri Perkins Tibbi Ara\u015fd\u0131rmalar \u0130nstitutunun aliml\u0259ri a\u015fkar edibl\u0259r ki, bal ar\u0131s\u0131 z\u0259h\u0259rind\u0259ki bir madd\u0259 d\u00f6\u015f x\u0259r\u00e7\u0259ngin\u0259 qar\u015f\u0131 “son d\u0259r\u0259c\u0259 g\u00fccl\u00fc” bir silah olaraq istifad\u0259 edil\u0259 bil\u0259r. ARANTV.AZ\u00a0 x\u0259b\u0259r verir ki, k\u0259\u015ffin m\u00fc\u0259llifl\u0259ri son bir…","_links":{"self":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts\/215957"}],"collection":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=215957"}],"version-history":[{"count":0,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts\/215957\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/media\/215958"}],"wp:attachment":[{"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=215957"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=215957"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=215957"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}