{"id":80614,"date":"2019-09-23T09:37:14","date_gmt":"2019-09-23T06:37:14","guid":{"rendered":"http:\/\/arantv.az\/?p=80614"},"modified":"2019-09-23T09:37:14","modified_gmt":"2019-09-23T06:37:14","slug":"x%c9%99rc%c9%99ngin-mualic%c9%99sind%c9%99-inqilabi-yenilik","status":"publish","type":"post","link":"https:\/\/arantv.az\/?p=80614","title":{"rendered":"X\u0259r\u00e7\u0259ngin m\u00fcalic\u0259sind\u0259 inqilabi – YEN\u0130L\u0130K"},"content":{"rendered":"

AB\u015e-\u0131n Stenford Universitetinin aliml\u0259ri CAR T- h\u00fcceyr\u0259 terapiyas\u0131n\u0131 x\u0259r\u00e7\u0259ng immunoterapiyas\u0131 sah\u0259sind\u0259 inqilabi bir yenilik adland\u0131r\u0131blar.<\/p>\n

Bu bar\u0259d\u0259\u00a0\u201cMedicalXpress\u201d<\/a>in m\u0259lumat\u0131nda bildirilib.<\/p>\n

T\u0259dqiqat\u00e7\u0131lar \u0259ld\u0259 olunmu\u015f klinik m\u0259lumatlara \u0259sas\u0259n\u00a0terapiyan\u0131n effektivliyini qiym\u0259tl\u0259ndiribl\u0259r.<\/p>\n

<\/div>\n

Aliml\u0259rin fikrinc\u0259, CAR T- h\u00fcceyr\u0259 terapiyas\u0131 m\u00fcalic\u0259y\u0259 cavab verm\u0259y\u0259n b\u0259dxass\u0259li \u015fi\u015fl\u0259rin n\u00f6vl\u0259ri il\u0259 m\u00fcbariz\u0259d\u0259 bel\u0259 effektiv n\u0259tic\u0259 verib. Bununla bel\u0259, qeyd olunur ki, bu metod m\u00fcr\u0259kk\u0259bdir v\u0259 h\u0259mi\u015f\u0259 k\u00f6m\u0259k etmir, \u00e7\u00fcnki x\u0259r\u00e7\u0259ngin b\u0259zi n\u00f6vl\u0259ri m\u00fcalic\u0259y\u0259 m\u00fcqavim\u0259t g\u00f6st\u0259rir. Lakin bu \u00e7at\u0131\u015fmazl\u0131qlar g\u0259l\u0259c\u0259kd\u0259 aradan qald\u0131r\u0131la bil\u0259r.<\/p>\n

M\u00fct\u0259x\u0259ssisl\u0259r x\u0259st\u0259l\u0259rin 60-93 faizind\u0259 terapiyan\u0131n effektiv oldu\u011funu t\u0259sbit edibl\u0259r. \u00c7ox vaxt o, V h\u00fcceyr\u0259l\u0259rinin k\u0259skin lenfoblastik leykozunda da effekt g\u00f6st\u0259rir. Bel\u0259 ki, uzunm\u00fcdd\u0259tli m\u00fc\u015fahid\u0259l\u0259r x\u0259st\u0259liyin t\u0259krarlana bil\u0259c\u0259yini d\u0259 g\u00f6st\u0259rib.<\/p>\n

V- b\u00f6y\u00fck h\u00fcceyr\u0259 limfomas\u0131nda metod h\u0259r zaman i\u015fl\u0259mir, lakin tr\u0259krarlanma ehtimal\u0131 azd\u0131r. Bu is\u0259 x\u0259st\u0259liyin eyni g\u00f6st\u0259ricil\u0259rl\u0259 uzunm\u00fcdd\u0259tli m\u00fcalic\u0259sin\u0259 g\u0259tirib \u00e7\u0131xar\u0131r.<\/p>\n

CAR T- h\u00fcceyr\u0259 terapiyas\u0131nda ximerik antigen reseptoru istifad\u0259 olunur. O, immunitet sistemini aktivl\u0259\u015fdir\u0259n x\u00fcsusi antitel v\u0259 domenl\u0259r\u0259 se\u00e7ici \u015f\u0259kild\u0259 ba\u011flanan antitel par\u00e7as\u0131n\u0131 birl\u0259\u015fdir\u0259n proteindir.<\/p>\n

X\u0259st\u0259nin x\u0259r\u00e7\u0259ng h\u00fcceyr\u0259l\u0259rind\u0259ki CD19 z\u00fclal\u0131 il\u0259 \u0259laq\u0259li ximerik antigenik reseptor CAR oldu\u011fundan onun T h\u00fcceyr\u0259l\u0259ri \u00e7\u0131xar\u0131l\u0131r v\u0259 genetik olaraq d\u0259yi\u015fdirilir. Modifikasiyadan sonra is\u0259 onlar yenid\u0259n x\u0259st\u0259nin b\u0259d\u0259nin\u0259 daxil edilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

AB\u015e-\u0131n Stenford Universitetinin aliml\u0259ri CAR T- h\u00fcceyr\u0259 terapiyas\u0131n\u0131 x\u0259r\u00e7\u0259ng immunoterapiyas\u0131 sah\u0259sind\u0259 inqilabi bir yenilik adland\u0131r\u0131blar. Bu bar\u0259d\u0259\u00a0\u201cMedicalXpress\u201din m\u0259lumat\u0131nda bildirilib. T\u0259dqiqat\u00e7\u0131lar \u0259ld\u0259 olunmu\u015f klinik m\u0259lumatlara \u0259sas\u0259n\u00a0terapiyan\u0131n effektivliyini qiym\u0259tl\u0259ndiribl\u0259r. Aliml\u0259rin fikrinc\u0259, CAR T- h\u00fcceyr\u0259 terapiyas\u0131 m\u00fcalic\u0259y\u0259 cavab verm\u0259y\u0259n b\u0259dxass\u0259li \u015fi\u015fl\u0259rin n\u00f6vl\u0259ri il\u0259 m\u00fcbariz\u0259d\u0259 bel\u0259 effektiv n\u0259tic\u0259 verib. Bununla bel\u0259, qeyd olunur ki, bu metod m\u00fcr\u0259kk\u0259bdir v\u0259 h\u0259mi\u015f\u0259 k\u00f6m\u0259k etmir, \u00e7\u00fcnki x\u0259r\u00e7\u0259ngin b\u0259zi n\u00f6vl\u0259ri m\u00fcalic\u0259y\u0259 m\u00fcqavim\u0259t g\u00f6st\u0259rir. Lakin bu \u00e7at\u0131\u015fmazl\u0131qlar g\u0259l\u0259c\u0259kd\u0259 aradan qald\u0131r\u0131la bil\u0259r. M\u00fct\u0259x\u0259ssisl\u0259r x\u0259st\u0259l\u0259rin 60-93 faizind\u0259 terapiyan\u0131n effektiv oldu\u011funu t\u0259sbit edibl\u0259r. \u00c7ox vaxt o, V h\u00fcceyr\u0259l\u0259rinin k\u0259skin lenfoblastik leykozunda da effekt…<\/p>\n","protected":false},"author":2,"featured_media":80615,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"categories":[1],"tags":[],"aioseo_notices":[],"gutentor_comment":0,"rttpg_featured_image_url":{"full":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"landscape":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"portraits":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"thumbnail":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht-150x150.jpg",150,150,true],"medium":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht-300x169.jpg",300,169,true],"large":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"1536x1536":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"2048x2048":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false],"post-thumbnail":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht-240x172.jpg",240,172,true],"advps-thumb-one":["https:\/\/arantv.az\/wp-content\/uploads\/2019\/09\/thnfht.jpg",620,349,false]},"rttpg_author":{"display_name":"V\u00fcsal Rafiqo\u011flu","author_link":"https:\/\/arantv.az\/?author=2"},"rttpg_comment":0,"rttpg_category":"C\u0259miyy\u0259t<\/a>","rttpg_excerpt":"AB\u015e-\u0131n Stenford Universitetinin aliml\u0259ri CAR T- h\u00fcceyr\u0259 terapiyas\u0131n\u0131 x\u0259r\u00e7\u0259ng immunoterapiyas\u0131 sah\u0259sind\u0259 inqilabi bir yenilik adland\u0131r\u0131blar. Bu bar\u0259d\u0259\u00a0\u201cMedicalXpress\u201din m\u0259lumat\u0131nda bildirilib. T\u0259dqiqat\u00e7\u0131lar \u0259ld\u0259 olunmu\u015f klinik m\u0259lumatlara \u0259sas\u0259n\u00a0terapiyan\u0131n effektivliyini qiym\u0259tl\u0259ndiribl\u0259r. Aliml\u0259rin fikrinc\u0259, CAR T- h\u00fcceyr\u0259 terapiyas\u0131 m\u00fcalic\u0259y\u0259 cavab verm\u0259y\u0259n b\u0259dxass\u0259li \u015fi\u015fl\u0259rin n\u00f6vl\u0259ri il\u0259 m\u00fcbariz\u0259d\u0259 bel\u0259 effektiv n\u0259tic\u0259 verib. Bununla bel\u0259, qeyd olunur ki, bu metod m\u00fcr\u0259kk\u0259bdir v\u0259 h\u0259mi\u015f\u0259…","_links":{"self":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts\/80614"}],"collection":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=80614"}],"version-history":[{"count":0,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/posts\/80614\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=\/wp\/v2\/media\/80615"}],"wp:attachment":[{"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=80614"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=80614"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arantv.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=80614"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}